RN Programs in South Carolina

Learn how to become an RN in South Carolina, including requirements, accredited programs, salary, and job outlook.
Best RN Programs in South Carolina: Top 30 Choices in 2025

Are you a high school senior, displaced worker, or simply someone in South Carolina looking for a new and exciting career? Does an average salary of $81,390 per year sound appealing? If so, a career as a Registered Nurse (RN) may be perfect for you. There is a high demand for RNs in South Carolina, and you can train for an entry-level position in just two or three years.

Requirements to Become an RN in South Carolina

Earning an associate's degree in nursing from an accredited school will give you the skills and knowledge you need to pass your licensing exam. The NCLEX-RN, a national exam that is also required in South Carolina, consists of a written test and a clinical assessment of your nursing knowledge and skills. You must pass this exam to obtain an RN license in South Carolina.

After completing the required training and passing your licensing exam, apply for an RN license from the South Carolina Department of Labor, Licensing, and Regulation. You will also need to have a valid driver's license or state ID and pass a background check.

Accredited RN Programs in South Carolina

South Carolina is home to many excellent schools that offer training for aspiring RN students. Here are a few of the finest:

  1. Aiken Technical College

    2276 Jefferson Davis Hwy, Graniteville, SC 29829
    (803) 593-9231
  2. Anderson University

    316 Boulevard, Anderson, SC 29621
    (864) 231-2000
  3. Bob Jones University

    1700 Wade Hampton Blvd, Greenville, SC 29614
    (864) 242-5100
  4. Central Carolina Tech College

    506 N Guignard Dr, Sumter, SC 29150
    (803) 778-1961
  5. Charleston Southern University

    9200 University Blvd, North Charleston, SC 29406
    (843) 863-7000
  6. Clemson University

    School of Nursing, 508 Edwards, Clemson, SC 29634
    (864) 656-3311
  7. ECPI Greenville

    1001 Keys Dr #100, Greenville, SC 29615
    (864) 438-5018
  8. ECPI University - Charleston

    3800 Paramount Dr, North Charleston, SC 29405
    (843) 606-5902
  9. Florence-Darlington Technical College

    2715 W Lucas St, Florence, SC 29501
    (843) 661-8140
  10. Fortis College in Columbia

    246 Stoneridge Dr Suite 101, Columbia, SC 29210
    (803) 678-4800
  11. Francis Marion University

    221 Cherokee Rd, Florence, SC 29501
    (843) 661-1362
  12. Greenville Technical College

    506 S Pleasantburg Dr, Greenville, SC 29607
    (864) 250-8000
  13. Horry Georgetown Technical College

    2050 US-501, Conway, SC 29526
    (843) 347-3186
  14. Lander University

    320 Stanley Ave, Greenwood, SC 29649
    (864) 388-8000
  15. Medical University of South Carolina

    99 Jonathan Lucas St, Charleston, SC 29425
    (843) 792-8515
  16. Midlands Technical College

    151 Powell Rd, Columbia, SC 29203
    (803) 738-8324
  17. Newberry College

    2100 College St, Newberry, SC 29108
    (800) 845-4955
  18. Orangeburg-Calhoun Technical College

    3250 St Matthews Rd, Orangeburg, SC 29118
    (803) 536-0311
  19. Piedmont Technical College

    620 Emerald Rd N, Greenwood, SC 29646
    (800) 868-5528
  20. Spartanburg Community College

    107 Community College Drive, Spartanburg, SC 29303
    (864) 592-4600
  21. Technical College of the Lowcountry

    921 Ribaut Rd, Beaufort, SC 29902
    (843) 525-8211
  22. The Citadel

    171 Moultrie St, Charleston, SC 29409
    (843) 225-3294
  23. Tri-County Technical College

    7900 US-76, Pendleton, SC 29670
    (864) 646-1338
  24. Trident Technical College

    7000 Rivers Ave, North Charleston, SC 29406
    (843) 574-6111
  25. University of South Carolina - Beaufort

    805 Carteret St, Beaufort, SC 29902
    (843) 521-4100
  26. University of South Carolina - Columbia

    Williams-Brice Building, 1601 Greene St, Columbia, SC 02920
    (803) 777-7412
  27. University of South Carolina - Upstate

    800 University Way, Spartanburg, SC 29303
    (864) 503-5440
  28. University of South Carolina Aiken

    471 University Pkwy, Aiken, SC 29801
    (803) 648-6851
  29. Williamsburg Technical College

    601 Martin Luther King Jr Ave, Kingstree, SC 29556
    (843) 355-4110
  30. York Technical College

    452 Anderson Rd S, Rock Hill, SC 29730
    (803) 327-8000

RN Job Outlook and Salary in South Carolina

South Carolina RNs are in high demand, with Projections Central forecasting a 9.9% job growth rate from 2022 to 2032. According to the U.S. Bureau of Labor Statistics, RNs in South Carolina earn an average annual salary of $81,390 per year, equivalent to $39.1 per hour.

The following table shows the total number of RNs employed in South Carolina, and their average wage and salary, by area.

AreaTotal EmploymentAvg Hourly WageAvg Annual Salary
Florence3,030$44.6$92,840
Charleston-North Charleston9,630$41.3$86,010
Columbia8,740$38.8$80,790
Greenville-Anderson-Mauldin9,330$38.0$79,210
Sumter720$38.0$79,140
Spartanburg4,420$37.0$77,120
Myrtle Beach-Conway-North Myrtle Beach3,110$36.6$76,310
Hilton Head Island-Bluffton-Beaufort1,280$36.0$74,970

Source: U.S. Bureau of Labor Statistics (BLS)

South Carolina Board of Nursing

The South Carolina Board of Nursing is the primary resource for RNs in South Carolina for all nursing-related questions and concerns.

South Carolina Board of Nursing

110 Centerview Dr #202, Columbia, SC 29210
(803) 896-4550
(803) 896-4515

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